Pedippi® Frequently asked questions

Yes, Pedippi can be diluted with a little milk (20-30 ml).

Lareb's advice: Dilute omeprazole suspension Pedippi with milk

Parents who give their child Pedippi are advised to dilute the suspension with a small amount of milk. This is because the suspension is thick, which can cause problems for the child when swallowing.

The CBG has asked the manufacturer to include advice in the package leaflet to take the suspension with a small amount (20-30 ml) of milk.

Leaks can be caused by:

• the bottle has not been prepared correctly, for example if the colourless, transparent syringe adapter has not been properly attached to the bottle;
• the red ring has not been removed and the grey cap cannot be screwed fully onto the bottle. This can cause a small amount of suspension to enter the cap during shaking, which will then leak from the bottle when it is turned upside down

Remove the red ring if it is still on the bottle and clean the cap and the top of the bottle.

Make sure the top of the bottle is completely clean before screwing the grey cap back onto the bottle.

We recommend always storing the bottle upright in the refrigerator.

Yes, this medicine is suitable for children over 1 month old.

Information about the Pedippi reimbursement scheme can be found on the website of the implementing organisation, Stichting Terugbetalingsregelingen (Reimbursement Schemes Foundation): Hevoconsult.nl

Pedippi 2 mg/ml has a vanilla-mint flavour.

Yes, this medicine is sugar, gluten, lactose and alcohol-free.

Yes, this medicine is halal.

This medicine can be kept for 28 days after opening.

This medicine can be stored in its sealed packaging for up to 24 months. See the date on the packaging.

Pedippi 2mg/ml in liquid form (after preparation): Store in the refrigerator (2°C – 8°C). Store in the original packaging to protect it from light and moisture. Keep the bottle tightly closed. The prepared suspension can be stored for 28 days. After this time, any remaining suspension must be discarded. The suspension may be stored outside the refrigerator at below 25°C for a maximum of 2 of the 28 days.

This medicine is a suspension in liquid form (after preparation).

They are sweeteners.

No, this medicine does not contain aspartame, but it does contain sucralose, maltitol and mannitol.

Yes, this medicine can be given to diabetics.

The red mixing disc helps to mix the powders and the suspension. The red plastic mixing disc always remains in the suspension during use; do not attempt to remove it.

Yes, this medicine can also be administered via a tube through the nose (nasogastric tube (NG tube)) or via a tube through the skin directly into the stomach (percutaneous endoscopic gastrostomy tube (PEG tube)).

Before administering this medicine, ensure that the feeding tube is not blocked.

• Flush the feeding tube with 5 ml of water.
• Administer the correct dose of this medicine using a suitable syringe.
• Flush the feeding tube with 5 ml of water.

This medicine is suitable for use with plastic tubes (polyurethane and PVC nasogastric (NG) and percutaneous endoscopic gastrostomy (PEG) tubes) in sizes 6 Fr to 16 Fr. For the smallest diameter tubes (6 Fr), a smaller flushing volume of 2 ml can be used in very young children.

Yes, this is correct. It is only suitable for oral administration. A suitable syringe must be used.

1. Combine the powders from the cap and the bottle.
   1. Shake the bottle for 10 seconds to loosen the powder.
   2. Turn the red cap anticlockwise (see arrow on cap) until the seal is broken. The powder from the red cap will fall into the bottle with a red mixing disc.
   3. Turn the red cap back to its original position and tighten it securely.
2. Preparing the powder
   1. Shake the bottle vigorously for 10 seconds to mix the powders.
   2. Tap the bottom of the bottle three times on a hard, flat (horizontal) surface to ensure that all the powder is in the bottle and none is left in the cap.
   3. Remove the red cap from the bottle.
   4. Using a suitable measuring cup, add 64 ml of water (up to the line on the label).
   5. Tighten the red cap securely on the bottle and shake the bottle vigorously for 30 seconds.
3. Inserting the spray adapter
   1. Remove the red cap and red ring and discard them.
   2. Insert the colourless, transparent spray nozzle (spray adapter) into the bottle and close the bottle with the grey screw cap.
   3. Leave the bottle to stand for fifteen minutes to achieve the final composition (consistency).

If you experience any side effects, please contact your doctor or pharmacist. If you wish to report a side effect, please send an email to info@fagron.nl.

You can also report side effects via the Dutch Side Effects Centre Lareb, website: www.Lareb.nl. By reporting side effects, you can help us obtain more information about the safety of this medicine.

Pedippi is prepared at the pharmacy. 64 ml of water must be added. Tap water is suitable for preparing Pedippi.

The packaging does indeed state that at least 75 ml is available for administration, which is confusing.

When registering this liquid medicine, the manufacturer was obliged to state this in the package leaflet and on the packaging. The CBG-MEB assumes that some wastage must be taken into account for 28 daily doses. Hence the minimum of 75 ml. See also SmPC 6.5 and the package leaflet.

If your child spits out Pedippi because of the taste, you can try the following: Hold your child upright and squirt the measured dose in small amounts into your child's cheek pouch, or dilute the measured dose with a little milk (20-30 ml maximum).