Risk factors

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Education and guidance is crucial

Patients who stop an SSRI or SNRI abruptly or within days are at risk of experiencing withdrawal symptoms (20-78%).

The advice is to suggest a longer phase-out schedule with smaller dosage steps (table 3) to patients at higher risk of withdrawal symptoms.

Reference: Practical notes on multidisciplinary document

Risk factors withdrawal symptoms:

How to choose a schedule?

References:

 1 Practical notes on multidisciplinary document
2 Multidisciplinary document

Show document

Risk factors withdrawal symptoms:


Patients who stop taking an SSRI or SNRI abruptly or within a few days are at risk of experiencing withdrawal symptoms. This is known as antidepressant discontinuation syndrome (ADS)1

  • Flu-like symptoms
  • Sleep disturbances
  • Gastrointestinal problems
  • Sensation of electric shocks
  • Psychological complaints such as anxiety, depression and irritability
If severe withdrawal symptoms occur, it may be advisable to increase the dose again. This will be the lowest dose at which you did not experience severe withdrawal symptoms. This also helps to distinguish withdrawal symptoms from a relapse.2

References:

 1 Practical notes on multidisciplinary document
2  Multidisciplinary document

Show document

Minimum dose per antidepressant


References:

 1 Practical notes on multidisciplinary document

Show document
Let us know how we can better meet your needs and those of your patients.

More information?

Risk factors

Together for responsible advice
Go to assortment

Education and guidance is crucial

Patients who stop an SSRI or SNRI abruptly or within days are at risk of experiencing withdrawal symptoms (20-78%).

The advice is to suggest a longer phase-out schedule with smaller dosage steps (table 3) to patients at higher risk of withdrawal symptoms.

Reference: Practical notes on multidisciplinary document

Risk factors withdrawal symptoms:

How to choose a schedule?







































References:

 1 Practical notes on multidisciplinary document
2 Multidisciplinary document

Show document

Risk factors withdrawal symptoms:


Patients who stop taking an SSRI or SNRI abruptly or within a few days are at risk of experiencing withdrawal symptoms. This is known as antidepressant discontinuation syndrome (ADS)1

  • Flu-like symptoms
  • Sleep disturbances
  • Gastrointestinal problems
  • Sensation of electric shocks
  • Psychological complaints such as anxiety, depression and irritability
If severe withdrawal symptoms occur, it may be advisable to increase the dose again. This will be the lowest dose at which you did not experience severe withdrawal symptoms. This also helps to distinguish withdrawal symptoms from a relapse.2

References:

 1 Practical notes on multidisciplinary document
2  Multidisciplinary document

Show document

Minimum dose per antidepressant


References:

 1 Practical notes on multidisciplinary document

Show document
Let us know how we can better meet your needs and those of your patients.

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With over 400 pharmacists within Fagron, we are focused on providing a unique range of high-quality products based on scientific data and insights. The Fagron Brands are unique concepts developed by our R&D specialists to provide pharmacies and clients with exclusive pharmaceutical dosage forms and active pharmaceutical ingredients (APIs). We can provide solutions for all steps inside a compounding setting, either equipment, excipients, APIs, packaging, and much more.